Searchable abstracts of presentations at key conferences in endocrinology

ea0011p893 | Thyroid | ECE2006

Cytostatic effect of plitidepsin (AplidinTM) in human undifferentiated (anaplastic) thyroid carcinoma

Bravo Susana , garcia-renduelles Maria , Seoane Rafael , Dosil Vanesa , Cameselle Jose , Lopez-Lázaro Luis , Zalvide Juan , Barreiro Franci , Pombo Celia , Alvarez Clara

Undifferentiated thyroid carcinoma is a highly aggressive human cancer with poor prognosis. A strong association has been observed between undifferentiated thyroid carcinoma and TP53 mutations. Plitidepsin (AplidinTM) a novel anticancer compound from a sea tunicate, has been reported to induce apoptosis independently of TP53 status. We investigated the actions of plitidepsin in human thyroid cancer cells. initiallyexperiments using primary cultured cells from a d...

ea0070aep863 | Thyroid | ECE2020

Retrospective incidence of NIFTP. A large multicentre Iberic study of over 3000 neoplasms

Paja Miguel , Rosa Bella M. , Iglesias Carmela , Zafón Carles , Cameselle Jose M.l , Carnero Gemma , Póvoa Antónia , Ugalde Aitziber , Anda Emma , Fernández-Seara Pilar , Sánchez-Gómez Nancy M. , Quiceno Hernán , García-Pascual Lluis , González Clarisa , Blanco Concepción , Gómez de la Riva Inés , Capel Ismael , Mancha Isabel , Gallego Helena , Maravall Javier , Roselló Esther , Alcázar Victoria , Chao Montserrat , Lázaro Antonia , Lopez-Agulló Susana , Echeverría Saioa , Joaquín Paricio J. , Sanz Javier , Messeguer Pascual , Castaño Ángel

The newly created NIFTP category (non-invasive follicular thyroid neoplasm with papillary-like nuclear features) has had a notorious impact in the management of thyroid neoplasms. Its incidence appears to be higher in western countries than Asiatic, but there are few studies including more than one institution.Objectives: To evaluate retrospectively the incidence of NITFP in a multicentre study in two adjacent countries as well as to compare th...